The Hemolung is a safe and simple-to-use respiratory assist system that is expected to allow patients in acute respiratory failure to avoid intubation and mechanical ventilation. The Hemolung may also be used as a supplement to mechanical ventilation to shorten the amount of time patients spend on ventilators in the ICU. The dialysis-like system effectively supplements lung function through a single, small catheter, removing up 50% of retained carbon dioxide from the blood, while administering up to 25% of needed oxygen. The Hemolung device consists of a small cylindrical oxygenator that is approximately 4 inches in diameter. A cylindrical bundle of micro-porous hollow fiber membranes woven into a mat is wrapped in multiple layers around a central core. Oxygen flows through the hollow fiber membranes, while blood is circulated though the hollow fibber bundle. The core is spun at approximately 1000 RPM, dramatically enhancing gas exchange, as well as serving as a pump to move the blood through the external circuit. When the Hemolung console is activated, oxygen flows through the hollow fibers and is transferred into the blood, while carbon dioxide is transferred from the blood into the oxygen stream and carried away from the body. SiGenix designed the electronics for the Hemolung controller. The hardware consists of analog and digital I/O, serial interfaces, data logging, and Ethernet capabilities. All electronics design, circuit board layout, and prototype assembly were performed by SiGenix. The embedded controller software and the User Interface software were designed and developed at SiGenix.